Education
University of California, Davis Ph.D. Biochemistry (Molecular Biology), 1986
East China Normal University, Shanghai B.S. (Honors) Biology (Biochemistry), 1982
Professional Experience
Executive Director, Programme for Research in Epidemic Preparedness and Response (PREAPRE). 2021-present
Professor, Programme in Emerging Infectious Diseases, Duke-NUS Medical School. 2012- present
Director, Programme in Emerging Infectious Diseases, Duke-NUS Medical School. 2012 -2020
OCE Science Leader, CSIRO Australian Animal Health 2008 Laboratory, Geelong, Vic. 2008 - 2015
Senior Principal Research Scientist and project leader, CSIRO Australian Animal Health Laboratory, Geelong, Vic. 2004 – 2008
Project Leader, Australian Biosecurity Cooperative Research Centre for Emerging Infectious Diseases (AB-CRC), Brisbane, Qld. 2003 – 2010
Principal Research Scientist and project leader, CSIRO Australian Animal Health Laboratory, Geelong, Vic. 1996 – 2004
Senior Research Scientist and project leader, CSIRO Australian Animal Health Laboratory, Geelong, Vic. 1992 – 1996
Research Scientist, CSIRO Australian Animal Health Laboratory, Geelong, Vic. 1990 – 1992
Senior Research Officer, the Centre for Molecular Biology and Medicine, Monash University, Clayton, Vic. 1990 – 1990
Senior Tutor, Department of Biochemistry, Monash University, Clayton, Vic. 1989 – 1990
Postdoctoral Research Fellow, Department of Biochemistry, University of California, Davis. 1986 – 1989
Postgraduate Student, Department of Biochemistry, University of California, Davis. 1982 – 1986
Awards and Fellowships
2021 Winner of the President Science Award (PSA) Singapore
2021 Elected Fellow of the American Academy of Microbiology
2020 First Prize, SingHealth Duke-NUS Research Award, 2020
2020 NHG Research and Innovation Award
2014 Winner of Australian Eureka Prize for Infectious Disease Research
2014 Finalist, President Science Award (PSA) Singapore
2014 Finalist, Prime Minister Award for Science, Australia
2014 ASM Bazeley Orator, Melbourne
2013 CSIRO Chaiman’s Medal
2012 Gardner Lectureship by the European Society of Clinical Virology
2010 Elected Fellow of Australian Academy of Technological Sciences and Engineering
2008 CSIRO OCE Science Leader Award
2007 Finalist, Eureka Prize for Scientific Research
2006 CSIRO Award for Excellence in Partnership
PUBLICATIONS
Selected publications, a full list is available in Google Scholar (https://scholar.google.com.sg/citations?user=tNV4u0MAAAAJ&hl=en)
Gamage AM, Chan W, Zhu F, Lim YT, Long S, Ahn M, Tan CW, Foo RJH, Sia WR, Lim XF, He H, Zhai W, Anderson DE, Sobota RM, Dutertre C-A, Wang L-F. Single-cell transcriptome analysis of the in vivo response to viral infection in the cave nectar bat Eonycteris spelaea. Immunity 2022 55(11):2187-2205.e5. doi: 10.1016/j.immuni.2022.10.008.
Tan CW, Chia WN, Zhu F, Yong BE, Chantasrisawad N, Hwa S-H, Yeoh AY-Y, Lim BL, Yag WC, Pada SKMS, Tan SY, Jantarabenjakul W, Toh LK, Shen S, Zhang J, Mah YY, Chen VC-W, Chen MI-C, Wacharapluesadee S, Sigal A, Putcharoen O, Lye DC, Wang L-F. SARS-CoV-2 Omicron variant emerged under immune selection. Nat Microbiol 2022 7(11):1756-1761. doi: 10.1038/s41564-022-01246-1
Zhang X-A, Li H, Jiang F-C, Zhu F, Zhang Y-F, Chen J-J, Tan C-W, Anderson DE, Fan H, Dong L-Y, Li C, Zhang P-H, Li Y, Ding H, Fang L-Q, Wang L-F, Liu W. A zoonotic henipavirus in febrile patients in China. N Engl J Med. 2022. 387:470-472. DOI: 10.1056/NEJMc2202705
Tan CW, Chia WN, Young BE, Zhu F, Lim BL, Sia WR, Thein TL, Chen MI, Leo YS, Lye DC and Wang L-F (2021) Pan-Sarbecovirus Neutralizing Antibodies in BNT162b2-Immunized SARS-CoV-1 Survivors. N Engl J Med doi: 10.1056/NEJMoa2108453. PMID: 34407341.
Ahn M and Wang L-F (2021) Translation from bats to humans beyond infectious diseases. J Exp Med 218(9):e20211223. doi: 10.1084/jem.20211223.
Irving A, Ahn M, Goh G, Anderson AE, Wang L-F (2021) Lessons from the host defences of bats, a unique viral reservoir. Nature 589 (7842): 363-370. doi.org/10.1038/s41586-020-03128-0
Wang L-F, Gamage AM, Chan WOY, Hiller M and Teeling EC (2021) Decoding bat immunity: the need for a coordinated research approach. Nat Rev Immunol doi: 10.1038/s41577-021-00523-0.
Tan CW, Chia WN, Qin X, Liu P, Chen MI-C, Tiu C, Hu Z, Chen VC-W, Young BE, Sia WR, Tan Y-J, Foo R, Yi Y, Lye DC, Anderson DE, Wang, L.-F (2020) A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2-spike protein-protein interaction. Nat Biotech DOI: 10.1038/s41587-020-0631-z
Wang L-F, Anderson DE, Mackenzie JS, Merson MH (2020) From Hendra to Wuhan: what has been learned in responding to emerging zoonotic viruses. Lancet 395(10224):e33-e34. doi: 10.1016/S0140-6736(20)30350-0.
Ahn M, Anderson DE, Zhang Q, Tan CW, Lim BL, Luko K, Wen M, Chia WN, Mani S, Wang LC, Ng JHJ, Sobota RM, Dutertre C-A, Ginhoux F, Shi Z-L, Irving A and Wang L-F. (2019) Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. Nat Microbiol. doi: 10.1038/s41564-019-0371-3.
Zhang, G., Cowled, C., Shi, Z., Huang, Z., Bishop-Lilly, K.A., Fang, X., Wynne, J.W., Xiong, Z., Baker, M.L., Zhao, W., Tachedjian, M., Zhu, Y., Zhou, P., Jiang, X., Ng, J., Yang, L., Wu, L., Xiao, J., Feng, Y., Chen, Y., Sun, X., Zhang, Y., Marsh, G.A., Crameri, G., Broder, C.C., Frey, K.G., Wang, L.-F. and Wang, J. (2013) Comparative Analysis of Bat Genomes Provides Insight into the Evolution of Flight and Immunity. Science 339: 456-460.
Li, W., Shi, Z., Yu, M., Ren, W., Smith, C., Epstein, J.H., Wang, H., Crameri, G., Hu, Z., Zhang, H., Zhang, J., McEachern, J., Field, H., Daszak, P., Eaton, B.T., Zhang, S., and Wang, L.-F. (2005) Bats are natural reservoir of SARS-like coronaviruses. Science 310: 676-679.